Service request form

Please, complete all fields.
DATE OF REQUEST (yyyy/mm/dd)*
Date Format: YYYY slash MM slash DD
YOUR CONTACT INFORMATIONS
*
- Mrs
- Mr.
First and Last Name*
Email*
Phone Number*
You are working in:*
- An academic laboratory (Public Laboratory)
- A private company
Entitled your laboratory or company*
Entitled of your team or department*
Scientific themes of your laboratory or company (maximum 4 keywords)*
Complete address of your laboratory or company*
No. and street:*
Zip code:*
City*
Country*
YOUR PROJECT
Summary of your scientific project (2000 characters maximum, including space)*
Tick the appropriate platform and service choice (several possible choices)
- ESTEAM PARIS-SUD
Reprogramming and organoid engineering Platform - Research grade: Modeling of somatic and hereditary malignancies (solid tumor and hematology) (ESTeam Villejuif)
ESTEAM PARIS-SUD
- Generation of human IPSC lines via reprogramming from various starting cells-research grade and characterizations (international standards: pluripotency assays, cell identity viability, sanitary tests)
- Generation of bioengineering of organoïds by 3D-culture methods from iPSC and progenitors (pathological models, toxicity and efficacy of advanced therapy medicinal products)
- Genome editing of IPSC lines and derived (Cells and organoids- pathological models)
- New cGMP Cell Factory Platform of IPSC and ATMPs bioproduction – clinical grade- for cellular therapy and immunotherapy (Cancers, Regenerative medicine) (ESTeam Evry)
Plateform BPF de Bioproduction de cellules IPSC
- Advanced manufacturing of safe, allogeneic and qualified cGMP-IPSC from haplotyped donors, universal or super-donors with international standards.
- Bioproduction of qualified cGMP-IPSC and derived cells by automated close system culture- Flexible Scale-out/ Scale-up of cGMP iPSC Bank stock.
- Evaluation of iPSC-derived cell therapy products with suitability standards for analytic tests (genomic integrity assays, immunogenicity, tumorigenicity, potency assays evaluating functionality, mode of action)
- Technological supports, specific automated equipment, access to cGMP clean rooms for technological co-development programs in bioproduction, design of new therapeutic tools / models and analytical tests
- I-STEM
Automated cell factory Platform of ESC/IPSC and derivatives- Research grade- for therapeutic molecular screening: Modeling of rare genetic diseases (Évry)
I-STEM
- Large scale and automated production of human pluripotent cells (hESC/hiPSC research grade) from healthy and/or mutation-bearing subjects (expert in rare diseases)
- Large scale and automated production of large banks of progeny derived from human pluripotent cells (hES/hiPS research grade) from healthy and/or mutation-bearing subjects (RPE, MSC, Keratinocytes, NSC)
- High and/or medium throughput screening of molecules with therapeutic potential
- IGBMC
High throughput molecular screening Platform for ESC/IPSC differentiation induction (Strasbourg)
IGBMC
- Cell-based assay development for high throughput screening
- siRNA-based and small molecule screening (cell-based assays)
- CRISPR-Cas9 pooled lentiviral screening (knockout, activation, repression) on Cas9 cell lines
- CRISPR/Cas9 genome-wide screening method
- PRIMASTEM/SBRI
Reprogramming and ESC derivation Platform of non-human primate for in vivo models (Lyon)
PRIMASTEM/SBRI
- Production of cynomolgus macaque (Macaca fascicularis) embryos by in vitro fertilization
- Production of macaque monkey (Macaca mulatta or Macaca fascicularis) iPSC lines
- Production of transgenic macaques using lentiviral vectors
- Pre-clinical model: Monkey macaque cynomolgus (Macaca fascicularis) + autologous iPSC line (biological validation, toxicity / biodistribution)
- SAFE-IPS
Reprogramming and organoid engineering Platform - Research grade: Modeling of aging diseases (Montpellier)
SAFE-IPS
- Production and characterization of human iPSC lines
- Characterization of IPSC lines: International standards: pluripotency assays, geno-identity, viability, sanitary tests
- Set up differentiation Protocols
- Production and characterization of organoïds
- Equipment rental dedicated to cell culture such as the Ruskin hood
- FORMATION
Organisation of practical technological training course (project hotel, sponsored workshop)
Formation
- Pluripotent stem cells culture methods and characterization:
  - Non-human primates (macaque, marmoset) (PrimaStem)
  - Human iPSC (ESTeam and SAFE-IPSC).
- Production and characterization of differentiated cells from iPSC: embryoid body, cardiac cells, mesenchymal stem cells, neural stem cells, definitive endoderm, other) (SAFE-iPS, I-STEM)
- Cellular high throughput screening (IGBMC)
Phone
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